Direct aziridination of a nitrostyrene is achieved upon treatment with an alkylamine and N-chlorosuccinimide. The reaction is initiated by the Michael addition of amine to nitroalkene. Subsequent N-chlorination and nucleophilic… Click to show full abstract
Direct aziridination of a nitrostyrene is achieved upon treatment with an alkylamine and N-chlorosuccinimide. The reaction is initiated by the Michael addition of amine to nitroalkene. Subsequent N-chlorination and nucleophilic substitution at the nitrogen atom afford 1-alkyl-2-nitroaziridine diastereoselectively. This reaction mechanism was clarified by NMR studies.
Keywords:
aziridination nitroalkenes;
aziridination;
mechanistic study;
study aziridination;
nitroalkenes mediated;
mediated chlorosuccinimide
Journal Title: Journal of oleo science
Year Published: 2022
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Journal Title: Journal of oleo science
Year Published: 2022
Link to full text (if available)
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recommendations!