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A Preparation Technique of Fine S/O/W Emulsions for Protein Delivery Formed with Solid Fat.

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The improvement in the stability of solid-in-oil-in-water (S/O/W) emulsions, which are used as carriers for protein delivery, was investigated. For this purpose, emulsions were prepared using trimyristin, a solid fat,… Click to show full abstract

The improvement in the stability of solid-in-oil-in-water (S/O/W) emulsions, which are used as carriers for protein delivery, was investigated. For this purpose, emulsions were prepared using trimyristin, a solid fat, as the oil phase, and using the membrane emulsification and solvent evaporation methods. The samples were made into stable fine emulsions using polyvinyl alcohol, a hydrophilic polymer, as an emulsifier, and by controlling the particle size uniformly. The S/O/W emulsions prepared by this method showed almost no leakage of encapsulated proteins and exhibited controlled release in an intestinal environment.

Keywords: solid fat; fine emulsions; protein delivery; technique fine; preparation technique

Journal Title: Journal of oleo science
Year Published: 2022

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