LAUSR

We acknowledge the dopamine hypothesis, but due to the constraints of the MJA snapshot format, this was not postulated or expanded on in our article. Clozapine is classified as a phenothiazine, which is a major class of antipsychotics with a well documented history of causing skin and ocular pigmentation. Borodoker and colleagues reported a case of long term thioridazine and chlorpromazine use associated with peripheral retinal hyperpigmentation and atrophic areas within the macula. Similarly, Lal and colleagues reported an association between long term chlorpromazine therapy and pigmentation of the corneal endothelium and anterior lens capsule. On ceasing chlorpromazine, most patients experienced a decrease in ocular and accompanying skin pigmentation.