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Absolute risk assessment for guiding cardiovascular risk management in a chest pain clinic

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In reply: We thank Blazak and Greaves1 for their comments on our article.2 In their letter, the authors noted the possible influence of bias from betweengroup differences in the baselinereported… Click to show full abstract

In reply: We thank Blazak and Greaves1 for their comments on our article.2 In their letter, the authors noted the possible influence of bias from betweengroup differences in the baselinereported use of antihypertensive and lipidlowering therapy. We want to highlight that we accounted for these covariables in the ANOVA models for the primary analysis. Nonetheless, we have undertaken further analysis, and this also confirms that the results are consistent regardless of whether antihypertensive or lipidlowering therapy was reported at baseline (Box). We propose that the mechanism for the modest improvement in blood pressure and cholesterol in the intervention arm is the adoption of lifestyle changes, supported by the noted improvement in body mass index and quality of life scores for this group. It is possible that adherence to prescribed medication may have differed between the groups at followup, and this remains an important focus of the approach provided by the rapid access chest pain clinic.

Keywords: chest pain; risk; absolute risk; pain clinic

Journal Title: Medical Journal of Australia
Year Published: 2021

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