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Keratinocyte cancer in chronic smokers: is this arsenic exposure?

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An 83yearold woman of European ancestry had an initial diagnostic consideration of arsenical keratosis in 2014 on the presumed background of childhood arsenic exposure reportedly from a cough mixture containing… Click to show full abstract

An 83yearold woman of European ancestry had an initial diagnostic consideration of arsenical keratosis in 2014 on the presumed background of childhood arsenic exposure reportedly from a cough mixture containing arsenic flakes. She disclosed smoking an average of ten cigarettes per day since she was 14 years old and reported a history of chronic obstructive pulmonary disease and dyslipidaemia, for which she received inhaled corticosteroids and statin therapy. She attended routine interval skin checks during an 8year period, when a surplus of 15 total basal cell carcinomas and squamous cell carcinomas were excised and confirmed with subsequent histopathological diagnosis. Both acitretin and nicotinamide were unsuccessfully trialled, alongside extensive photoprotection measures.

Keywords: keratinocyte cancer; smokers arsenic; arsenic exposure; chronic smokers; cancer chronic; exposure

Journal Title: Medical Journal of Australia
Year Published: 2022

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