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Fecal Calprotectin as a Surrogate Marker for Mucosal Healing After Initiating the Therapeutic Anti-Tubercular Trial

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An aphthous ulcer and pseudopolyps cannot be used to distinguish between the two diseases. 4 Regarding cross-sec-tional imaging findings, computed tomography enterography or magnetic resonance enterography shows comb, target, and… Click to show full abstract

An aphthous ulcer and pseudopolyps cannot be used to distinguish between the two diseases. 4 Regarding cross-sec-tional imaging findings, computed tomography enterography or magnetic resonance enterography shows comb, target, and adipose creeping signs that significantly favor CD. Concur-rently, necrotic intra-abdominal lymph nodes greatly support ITB diagnosis. Regarding histopathological findings, patients with ITB are twice more likely to have granuloma than those with CD. 4 Some granuloma characteristics such as confluent, giant, and multiple granulomas significantly favor ITB. Many diagnostic models have been proposed to combine all crucial factors differentiating between the two intestinal diseases. 7 A scoring system with more parameters available has a better than that with less parameters. 7 A multicenter retrospective study conducted in Asia validated various models for distinguishing between ITB and CD and showed that the

Keywords: marker mucosal; surrogate marker; mucosal healing; fecal calprotectin; calprotectin surrogate; healing initiating

Journal Title: Clinical Endoscopy
Year Published: 2022

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