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The use of botulinum toxin type A to minimize scarring in cleft lip repair: A literature review

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Postsurgical scars can be a major concern for many patients. Young and Hutchison [1] found that patients were usually not satisfied with their surgical scars, with 91% stating that they… Click to show full abstract

Postsurgical scars can be a major concern for many patients. Young and Hutchison [1] found that patients were usually not satisfied with their surgical scars, with 91% stating that they would value any further improvement in their scars. Cleft lip with or without cleft palate is one of the most common congenital anomalies worldwide [2,3]. Nonsyndromic cleft lip/palate affects approximately 1.5 to 2.5 cases per 1,000 live births, and its epidemiological distribution varies by ethnicity and geographic area [4,5]. In today’s culture, there is a major emphasis on facial appearances, largely driven by advances in social media. Individuals with deviations from what is considered “a normal look” may be socially stigmatized in their communities. Therefore, the final facial scar appearance remains a significant concern for affected individuals and their families. Herein, we review the process of wound healing and summarize the literature evaluating the effects of botulinum toxin type A (BTA) on scar formation in cleft lip repair.

Keywords: toxin type; lip repair; review; cleft lip; lip; botulinum toxin

Journal Title: Archives of Plastic Surgery
Year Published: 2019

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