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Human Leukocyte Transcriptional Response to SARS-CoV-2 Infection

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It is necessary to elucidate why in the present coronavirus disease-19 (COVID-19) global pandemic infection by SARS-CoV-2 affects children, adults, and elderly people differently. Epidemiological and clinical data have shown… Click to show full abstract

It is necessary to elucidate why in the present coronavirus disease-19 (COVID-19) global pandemic infection by SARS-CoV-2 affects children, adults, and elderly people differently. Epidemiological and clinical data have shown that most children who test positive for SARS-CoV-2 are either asymptomatic or develop mild symptoms (-). Several hypotheses have been suggested to explain these findings: differences in the immune system of adults and children (and between very young children, pre-schooling children, and adolescents); competition with other respiratory viruses in the [...]

Keywords: infection; response sars; human leukocyte; leukocyte transcriptional; sars cov; transcriptional response

Journal Title: Clinics
Year Published: 2020

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