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Synthesis of the linear octaarabinofuranoside related to the terminal fragment of mycobacterial polysaccharides

A convergent synthesis of linear α-(1→5)-, β-(1→2)-linked octaarabinofuranoside related to the terminal fragment of mycobacterial polysaccharides was performed using a [6+2] scheme. The octaarabinofuranoside was obtained as a 4-(2-azidoethoxy)phenyl glycoside… Click to show full abstract

A convergent synthesis of linear α-(1→5)-, β-(1→2)-linked octaarabinofuranoside related to the terminal fragment of mycobacterial polysaccharides was performed using a [6+2] scheme. The octaarabinofuranoside was obtained as a 4-(2-azidoethoxy)phenyl glycoside which can be further converted to neoglycoconjugates that are important for the development of diagnostic tools.

Keywords: terminal fragment; octaarabinofuranoside related; mycobacterial polysaccharides; synthesis linear; fragment mycobacterial; related terminal

Journal Title: Mendeleev Communications
Year Published: 2025

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