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Summary for Patients: Preconception Antidiabetic Drugs in Men and Birth Defects in Offspring

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What is the problem and what is known about it so far? Poorly controlled diabetes can reduce sperm quality. However, the effects of diabetes medications on sperm quality are uncertain.… Click to show full abstract

What is the problem and what is known about it so far? Poorly controlled diabetes can reduce sperm quality. However, the effects of diabetes medications on sperm quality are uncertain. Information is lacking about the risk for birth defects in babies born to fathers with diabetes. If birth defects were more common with some diabetes medications, birth outcomes could potentially be improved if men with diabetes switched to other diabetes medications when trying to father a child.

Keywords: preconception antidiabetic; birth; summary patients; birth defects; patients preconception; diabetes medications

Journal Title: Annals of Internal Medicine
Year Published: 2022

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