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Aortic stenosis (AS) is the most common valvular disorder frequently affecting patients as they get older, and resulting in life-altering symptoms such as dyspnea, angina, pre-syncope, and syncope, which are… Click to show full abstract
Aortic stenosis (AS) is the most common valvular disorder frequently affecting patients as they get older, and resulting in life-altering symptoms such as dyspnea, angina, pre-syncope, and syncope, which are often made worse with exertion. Often, AS is caused by age-related calcification of the valve; in addition, its pathogenetic mechanism also involves the fact that bicuspid aortic valves tend to narrow rapidly compared to other three-leaflet valve. As the aging population continues to grow, an increasing number of patients are seeking treatment for AS, which makes therapies for AS continuing to evolve and improve.
Journal Title: Journal of Biomedical Research
Year Published: 2022
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