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A Case of AB Para-Bombay Phenotype with Weak A Antigen Expression.

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BACKGROUND The Para-Bombay phenotype is characterized by H antigen partially or totally deficient on red blood cells and the presence of ABH substances in body fluids. METHODS A patient with… Click to show full abstract

BACKGROUND The Para-Bombay phenotype is characterized by H antigen partially or totally deficient on red blood cells and the presence of ABH substances in body fluids. METHODS A patient with discrepant results in forward and reverse ABO phenotyping was further investigated by serological and molecular methods. RESULTS Ortho gel and tube results showed weak A antigen expression and weak antibody reacting with A and B cells. Absorption-elution assay detected B antigen, and saliva test confirmed substances H were present. The patient was confirmed as A102B101 and Le(a+b+) phenotype. CONCLUSIONS These findings suggest that the case is AB Para-Bombay Phenotype (secretor).

Keywords: bombay phenotype; antigen; para bombay; phenotype

Journal Title: Clinical laboratory
Year Published: 2021

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