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Lesson of the month 1: Lemierre's syndrome a reminder of the ‘forgotten disease’

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ABSTRACT Lemierre’s syndrome is a condition characterised by suppurative thrombophlebitis of the internal jugular (IJ) vein following a recent oropharyngeal infection, with resulting septicaemia and metastatic lesions. It is strongly… Click to show full abstract

ABSTRACT Lemierre’s syndrome is a condition characterised by suppurative thrombophlebitis of the internal jugular (IJ) vein following a recent oropharyngeal infection, with resulting septicaemia and metastatic lesions. It is strongly associated with Fusobacterium necrophorum, a Gram-negative bacilli. Key to early diagnosis is awareness of the classical history and course of this illness, and therefore to ask about a history of recent oropharyngeal infections when a young patient presents with fever and rigors. Diagnosis can be confirmed by showing thrombophlebitis of the IJ vein, culturing F necrophorum from normally sterile sites or demonstrating metastatic lesions in this clinical setting. The cornerstone of management is draining of purulent collection where possible and prolonged courses of appropriate antibiotics. In this article, we review a case study of a young man with Lemierre’s syndrome and discuss the condition in more detail.

Keywords: lesson month; reminder forgotten; month lemierre; syndrome reminder; lemierre syndrome; forgotten disease

Journal Title: Clinical Medicine
Year Published: 2018

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