THE DNA-BASED THERAPEUTIC AGENT BC 007 COMPLETELY NEUTRALIZES AGONISTIC AUTOANTIBODIES DIRECTED AGAINST β1-ADRENOCEPTORS: RESULTS OF A PHASE 1 TRIAL
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DOI: 10.1016/s0735-1097(18)31186-0
Abstract: 80 percent of patients with non-ischemic heart failure (HF) and reduced ejection fraction have autoantibodies against β1-adrenoceptos (β1-AAB), which cause and/or sustain HF. The removal of β1-AAB by immunoadsorption (IA) leads to an improvement of… read more here.
Keywords: therapeutic agent; dna based; completely neutralizes; 007 completely ... See more keywords