PO-033 Identification and functional evaluation of monoclonal antibodies specifically targeting human carbonic anhydrase IX
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DOI: 10.1136/esmoopen-2018-eacr25.568
Abstract: Introduction Poor vascularisation of solid tumours leads to inadequate nutrient and oxygen supplies which forces tumour cells to reprogram their metabolism. As a consequence the tumour cell’s environment becomes acidic and hypoxic. This, in turn,… read more here.
Keywords: functional evaluation; carbonic anhydrase; 033 identification; monoclonal antibodies ... See more keywords
Abstract 033: Identification of s Primary Renal AT 2 Receptor Defect in Spontaneously Hypertensive Rats (SHR)
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DOI: 10.1161/hyp.72.suppl_1.033
Abstract: Angiotensin III (Ang III) [des-aspartyl1-Ang II] is the predominant endogenous agonist for angiotensin type-2 receptor (AT2R)-induced natriuresis in rats. Hypertensive 12 wk-old SHR lack natriureti... read more here.
Keywords: identification primary; 033 identification; primary renal; renal receptor ... See more keywords