Articles with "06409577 activates" as a keyword



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PF-06409577 Activates AMPK Signaling and Inhibits Osteosarcoma Cell Growth

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Published in 2021 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2021.659181

Abstract: Osteosarcoma (OS) is a common primary bone malignancy. We here investigated the potential activity of PF-06409577, a novel, potent, and direct activator of AMP-activated protein kinase (AMPK), against human OS cells. In established (U2OS, MG-63,… read more here.

Keywords: cell growth; activates ampk; activation; 06409577 activates ... See more keywords