Preclinical evaluation of LX-086, a small molecule as a selective inhibitor of PI3K.
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DOI: 10.1200/jco.2020.38.15_suppl.e15662
Abstract: e15662Background: PI3K/Akt signaling pathway plays a key role in a series of cellular functions related to cell growth, proliferation, survival and differentiation. PI3Kα is ubiquitously expressed,... read more here.
Keywords: selective inhibitor; preclinical evaluation; 086 small; molecule selective ... See more keywords