Articles with "099 facilitates" as a keyword



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URMC-099 facilitates amyloid-β clearance in a murine model of Alzheimer’s disease

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Published in 2018 at "Journal of Neuroinflammation"

DOI: 10.1186/s12974-018-1172-y

Abstract: BackgroundThe mixed lineage kinase type 3 inhibitor URMC-099 facilitates amyloid-beta (Aβ) clearance and degradation in cultured murine microglia. One putative mechanism is an effect of URMC-099 on Aβ uptake and degradation. As URMC-099 promotes endolysosomal protein… read more here.

Keywords: model alzheimer; urmc 099; facilitates amyloid; 099 facilitates ... See more keywords