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27 Quisinostat, a Potent Histone Deacetylase Inhibitor, Regulates the Expression of Pluripotency- and Reprogramming-Related Genes on Somatic Cell Nuclear Transferred Porcine Embryos

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Published in 2018 at "Reproduction, Fertility and Development"

DOI: 10.1071/rdv30n1ab27

Abstract: The low efficiency of somatic cell nuclear transfer (SCNT) has been attributed mostly to inefficient epigenetic reprogramming. Recently, various histone deacetylase inhibitors (HDACi) were used to improve developmental competence of SCNT embryos in several species.… read more here.

Keywords: 100 jnj; embryos; jnj; pluripotency reprogramming ... See more keywords