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Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.863959
Abstract: REL-1017 (esmethadone; dextromethadone; (S)-methadone) is the opioid-inactive dextro-isomer of the racemic mixture, (R, S)-methadone. REL-1017 acts as a low affinity, low potency N-methyl-D-aspartate receptor (NMDAR) channel blocker with rapid, robust, and sustained therapeutic effects in…
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Keywords:
sprague dawley;
rel 1017;
1017 esmethadone;
rel ... See more keywords