GM-1020: a novel, orally bioavailable NMDA receptor antagonist with rapid and robust antidepressant-like effects at well-tolerated doses in rodents
Sign Up to like & getrecommendations! Published in 2024 at "Neuropsychopharmacology"
DOI: 10.1038/s41386-023-01783-1
Abstract: The NMDA receptor (NMDAR) antagonist ketamine has shown great potential as a rapid-acting antidepressant; however, its use is limited by poor oral bioavailability and a side effect profile that necessitates in-clinic dosing. GM-1020 is a… read more here.
Keywords: orally bioavailable; antagonist; nmda receptor; 1020 novel ... See more keywords