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Dexmedetomidine Mitigates Microglial Activation Associated with Postoperative Cognitive Dysfunction by Modulating the MicroRNA-103a-3p/VAMP1 Axis

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Published in 2022 at "Neural Plasticity"

DOI: 10.1155/2022/1353778

Abstract: Surgery-induced microglial activation is critical in mediating postoperative cognitive dysfunction (POCD) in elderly patients, where the important protective effect of dexmedetomidine has been indicated. However, the mechanisms of action of dexmedetomidine during the neuroinflammatory response… read more here.

Keywords: 103a vamp1; microglial activation; mir 103a; postoperative cognitive ... See more keywords