Altered paracellular cation permeability due to a rare CLDN10B variant causes anhidrosis and kidney damage
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DOI: 10.1371/journal.pgen.1006897
Abstract: Claudins constitute the major component of tight junctions and regulate paracellular permeability of epithelia. Claudin-10 occurs in two major isoforms that form paracellular channels with ion selectivity. We report on two families segregating an autosomal… read more here.
Keywords: claudin; causes anhidrosis; permeability; 10b n48k ... See more keywords