Articles with "116 novel" as a keyword



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VI-116, A Novel Potent Inhibitor of VRAC with Minimal Effect on ANO1

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23095168

Abstract: Volume-regulated anion channel (VRAC) is ubiquitously expressed and plays a pivotal role in vertebrate cell volume regulation. A heterologous complex of leucine-rich repeat containing 8A (LRRC8A) and LRRC8B-E constitutes the VRAC, which is involved in… read more here.

Keywords: effect; potent; inhibitor; inhibitor vrac ... See more keywords