Articles with "11c ima107" as a keyword



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Imaging phosphodiesterase‐10a availability in cocaine use disorder with [11C]IMA107 and PET

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Published in 2019 at "Synapse"

DOI: 10.1002/syn.22070

Abstract: Phosphodiesterase‐10a (PDE10a) is located exclusively in medium spiny neurons (MSN). Rodent studies show an increase in striatal MSN spine density following exposure to cocaine. These increases in MSN spine density are suggested to underlie neurobiological… read more here.

Keywords: 11c ima107; cocaine use; phosphodiesterase 10a; cocaine ... See more keywords