Significance of 11C-PIB PET/CT in cardiac amyloidosis compared with 99mTc-aprotinin scintigraphy: A pilot study
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Nuclear Cardiology"
DOI: 10.1007/s12350-018-1260-5
Abstract: AbstractBackgroundThis study was to investigate the significance of 11C-Pittsburgh B (PIB) PET/CT in patients with suspected cardiac amyloidosis compared with 99mTc-aprotinin scintigraphy. MethodsThirteen consecutive patients with suspected cardiac amyloidosis were considered for enrolment in this… read more here.
Keywords: 99mtc aprotinin; study; 11c pib; amyloidosis ... See more keywords
Brain amyloid PET interpretation approaches: from visual assessment in the clinic to quantitative pharmacokinetic modeling
Sign Up to like & getrecommendations! Published in 2017 at "Clinical and Translational Imaging"
DOI: 10.1007/s40336-017-0257-4
Abstract: PurposeCerebral β-amyloid burden can be measured by positron emission tomography (PET) tracers, including 11C-Pittsburgh Compound B (11C-PiB) and three fluorinated tracers that have been approved by regulatory agencies. This review focuses on the current clinical… read more here.
Keywords: pharmacokinetic modeling; interpretation; 11c pib; amyloid pet ... See more keywords
Myelin imaging measures as predictors of cognitive impairment in MS patients: A hybrid PET-MRI study.
Sign Up to like & getrecommendations! Published in 2022 at "Multiple sclerosis and related disorders"
DOI: 10.1016/j.msard.2021.103331
Abstract: BACKGROUND Cognitive impairment is one of the concerns of Multiple Sclerosis (MS) and has been related to myelin loss. Different neuroimaging methods have been used to quantify myelin and relate it to cognitive dysfunctions, among… read more here.
Keywords: 11c pib; predictors cognitive; mtr; myelin imaging ... See more keywords
Comparison of longitudinal Aβ in nondemented elderly and Down syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2018.09.030
Abstract: Down syndrome (DS) predisposes individuals to early Alzheimer's disease (AD). Using Pittsburgh Compound B ([11C]PiB), a pattern of striatal amyloid beta (Aβ) that is elevated relative to neocortical binding has been reported, similar to that… read more here.
Keywords: nondemented elderly; compared nde; time; 11c pib ... See more keywords
Head-to-head comparison of 11C-PiB and 18F-FC119S for Aβ imaging in healthy subjects, mild cognitive impairment patients, and Alzheimer's disease patients
Sign Up to like & getrecommendations! Published in 2017 at "Medicine"
DOI: 10.1097/md.0000000000006441
Abstract: Abstract As a new beta amyloid (A&bgr;) positron emission tomography (PET) tracer, 18F-FC119S has shown higher cortical uptake in patients with Alzheimer's disease (AD) than that in healthy control subjects without adverse effects in a… read more here.
Keywords: 11c pib; 18f fc119s; fc119s pet;
A 5-year longitudinal evaluation in patients with mild cognitive impairment by 11C-PIB PET/CT: a visual analysis
Sign Up to like & getrecommendations! Published in 2019 at "Nuclear Medicine Communications"
DOI: 10.1097/mnm.0000000000001004
Abstract: Objective The aim of this study was to evaluate the cerebral amyloid distribution in patients with mild cognitive impairment (MCI), assessed by carbon-11-Pittsburgh compound B (11C-PIB) PET/CT, after 5 years of follow-up. Patients and methods… read more here.
Keywords: 11c pib; pib pet; pib retention; pib ... See more keywords
Can 11C-PiB-PET Relative Delivery R1 or 11C-PiB-PET Perfusion Replace 18F-FDG-PET in the Assessment of Brain Neurodegeneration?
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Alzheimer's Disease"
DOI: 10.3233/jad-180274
Abstract: Background: Pittsburgh Compound B (PiB) positron emission tomography (PET) is used to visualize in vivo amyloid plaques in the brain. Frequently the PiB examinations are complemented with a fluorodeoxyglucose (FDG) PET scan to further assess… read more here.
Keywords: pib; fdg pet; 11c pib; neurodegeneration ... See more keywords
An in vivo Pig Model for Testing Novel Positron Emission Tomography Radioligands Targeting Cerebral Protein Aggregates
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.847074
Abstract: Positron emission tomography (PET) has become an essential clinical tool for diagnosing neurodegenerative diseases with abnormal accumulation of proteins like amyloid-β or tau. Despite many attempts, it has not been possible to develop an appropriate… read more here.
Keywords: positron emission; brain; 11c pib; pig model ... See more keywords
Noninvasive Measurement of [11C]PiB Distribution Volume Using Integrated PET/MRI
Sign Up to like & getrecommendations! Published in 2020 at "Diagnostics"
DOI: 10.3390/diagnostics10120993
Abstract: A noninvasive image-derived input function (IDIF) method using PET/MRI was applied to quantitative measurements of [11C] Pittsburgh compound-B (PiB) distribution volume (DV) and compared with other metrics. Fifty-three patients suspected of early dementia (71 ±… read more here.
Keywords: 11c pib; distribution volume; pib distribution; pet mri ... See more keywords
In Vivo Preclinical Assessment of β-Amyloid–Affine [11C]C-PIB Accumulation in Aluminium-Induced Alzheimer’s Disease-Resembling Hypercholesterinaemic Rat Model
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232213950
Abstract: Aluminum (Al) excess and hypercholesterinaemia are established risks of Alzheimer’s disease (AD). The aim of this study was to establish an AD-resembling hypercholesterinaemic animal model—with the involvement of 8 week and 48 week-old Fischer-344 rats—by… read more here.
Keywords: amyloid affine; resembling hypercholesterinaemic; alzheimer disease; affine 11c ... See more keywords