Striatal Dopamine Release in Response to Morphine: A [11C]Raclopride Positron Emission Tomography Study in Healthy Men
Sign Up to like & getrecommendations! Published in 2019 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2019.03.965
Abstract: BACKGROUND Preclinical and human positron emission tomography studies have produced inconsistent results regarding the effects of opioids on mesolimbic dopamine (DA). Here, we quantify striatal DA release (measured by [11C]-raclopride displacement) in response to an… read more here.
Keywords: morphine; positron emission; emission tomography; 11c raclopride ... See more keywords
Effects of L-DOPA Monotherapy on Psychomotor Speed and [11C]Raclopride Binding in High-Risk Older Adults With Depression
Sign Up to like & getrecommendations! Published in 2019 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2019.04.007
Abstract: BACKGROUND A high-risk subgroup of older patients with depression has slowed processing and gait speeds. This study examined whether carbidopa/levodopa (L-DOPA) monotherapy increased dopamine availability, increased processing/gait speed, and relieved depressive symptoms. METHODS Adult outpatients… read more here.
Keywords: depression; gait speed; processing gait; 11c raclopride ... See more keywords
Low convergent validity of [11C]raclopride binding in extrastriatal brain regions: A PET study of within-subject correlations with [11C]FLB 457
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DOI: 10.1016/j.neuroimage.2020.117523
Abstract: Dopamine D2 receptors (D2-R) in extrastriatal brain regions are of high interest for research in a wide range of psychiatric and neurologic disorders. Pharmacological competition studies and test-retest experiments have shown high validity and reliability… read more here.
Keywords: 11c flb; flb 457; extrastriatal brain; brain regions ... See more keywords
Dopamine D2/D3 imbalance during migraine attack and allodynia in vivo
Sign Up to like & getrecommendations! Published in 2017 at "Neurology"
DOI: 10.1212/wnl.0000000000003861
Abstract: Objective: To evaluate in vivo the dynamics of endogenous dopamine (DA) neurotransmission during migraine ictus with allodynia. Methods: We examined 8 episodic migraineurs and 8 healthy controls (HC) using PET with [11C]raclopride. The uptake measure… read more here.
Keywords: attack; migraine; bpnd; 11c raclopride ... See more keywords
Measurement of Striatal Dopamine Release Induced by Neuropsychological Stimulation in Positron Emission Tomography With Dual Injections of [11C]Raclopride
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2022.811136
Abstract: Objectives Positron emission tomography (PET) with [11C]raclopride has been applied to measure changes in the concentration of endogenous dopamine induced by pharmacological challenge or neuropsychological stimulation by evaluating the binding potential (BP) between the baseline… read more here.
Keywords: injection; 11c raclopride; dual bolus; stimulation ... See more keywords