Articles with "122 pkm2" as a keyword



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Exosome‐delivered circRNA promotes glycolysis to induce chemoresistance through the miR‐122‐PKM2 axis in colorectal cancer

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Published in 2020 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12629

Abstract: Malignant tumors, including colorectal cancer (CRC), usually rely on ATP generation through aerobic glycolysis for both rapid growth and chemotherapy resistance. The M2 isoform of pyruvate kinase (PKM2) has a key role in catalyzing glycolysis,… read more here.

Keywords: glycolysis; pkm2; colorectal cancer; 122 pkm2 ... See more keywords