Histone deacetylase HDAC2 regulates microRNA‐125a expression in neuroblastoma
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2401
Abstract: Neuroblastoma (NB) is an infrequent childhood malignancy of the peripheral sympathetic nervous system and is accountable for about 10% of pediatric tumors. microRNA (miR)‐125a has been implicated to serve as a tumor suppressor in various… read more here.
Keywords: deacetylase hdac2; regulates microrna; microrna 125a; hdac2 regulates ... See more keywords
Triptolide ameliorates lupus via the induction of miR-125a-5p mediating Treg upregulation.
Sign Up to like & getrecommendations! Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2019.02.047
Abstract: Triptolide is a biologically active component of the Chinese antirheumatic herbal remedy Tripterygium wilfordii Hook F, which has been shown to be effective in treating murine lupus. However, its immunological mechanisms are poorly understood. Regulatory… read more here.
Keywords: triptolide; effect; 125a expression; mir 125a ... See more keywords
TIMP-1 downregulation modulates miR-125a-5p expression and triggers the apoptotic pathway
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.23832
Abstract: Matrix metalloproteinases and their natural inhibitors (TIMPs) are important elements in a wide range of oncology settings. Elevated levels of tissue inhibitor of metalloproteinase-1 (TIMP-1) have often been associated with increased tumorigenesis. This has been… read more here.
Keywords: timp downregulation; downregulation modulates; timp; 125a expression ... See more keywords