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TAK-242 Attenuates Crush Injury Induced Acute Kidney Injury through Inhibiting TLR4/NF-κB Signaling Pathways in Rats

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Published in 2020 at "Prehospital and Disaster Medicine"

DOI: 10.1017/s1049023x20001132

Abstract: Abstract Background: To investigate if toll-like receptor (TLR) 4/nuclear factor-kappa B (NF-κB) signaling pathways mediated crush injury induced acute kidney injury (AKI) in rats, and if TAK-242 (a specific inhibitor of TLR4) attenuates the injury… read more here.

Keywords: crush injury; tak 242; signaling pathways; injury ... See more keywords