Preparation and validation of cyclodextrin-based excipients for radioiodinated hypericin applied in a targeted cancer radiotherapy.
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DOI: 10.1016/j.ijpharm.2021.120393
Abstract: BACKGROUND Iodine-131 labeled hypericin (131I-Hyp) has been utilized as a necrosis-avid theragnostic tracer in a dual targeting pan-anticancer strategy called OncoCiDia. Widespread use of previously-tested solvent dimethyl sulfoxide (DMSO) is limited by safety concerns. To… read more here.
Keywords: microscopy; cyclodextrin; histopathology; 131i hyp ... See more keywords