Construction and Preclinical Evaluation of a 124/131I-labeled radiotracer for the Detection of Mesothelin-Overexpressing Cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.9b01281
Abstract: Mesothelin is a molecular biomarker of many types of solid cancers, which may represent a highly promising new target in the development of cancer-targeted diagnostic agents. A human anti-mesothelin antibody with a low molecular weight,… read more here.
Keywords: labeled radiotracer; 124 131i; mesothelin; 131i labeled ... See more keywords
131I-Caerin 1.1 and 131I-Caerin 1.9 for the treatment of non-small-cell lung cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.861206
Abstract: Objective To investigate the effect of the 131I-labeled high-affinity peptides Caerin 1.1 and Caerin 1.9 for the treatment of A549 human NSCLC cells. Methods ① 3-[4,5-Dimethylthiazole-2-yl]-2,5-diphenyltetrazolium bromide (MTT) and plate clone formation assays were performed… read more here.
Keywords: 131i labeled; caerin; 131i caerin; labeled caerin ... See more keywords