Radioiodinated Ethinylestradiol Derivatives for Estrogen Receptor Targeting Breast Cancer Imaging.
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DOI: 10.1021/acsmedchemlett.1c00559
Abstract: Two novel PEGylated ethinylestradiol (PEG = poly(ethylene glycol)) estrogen receptor (ER) targeting probes [131I]EITE and [131I]MITE were synthesized and evaluated. Both probes had a nanomolar binding affinity to the ER receptor (36.47 nM for [131I]EITE… read more here.
Keywords: breast; 131i eite; estrogen receptor; 131i mite ... See more keywords