Direct arterial injection of hyperpolarized 13C‐labeled substrates into rat tumors for rapid MR detection of metabolism with minimal substrate dilution
Sign Up to like & getrecommendations! Published in 2017 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.26628
Abstract: A rat model was developed to enable direct administration of hyperpolarized 13C‐labeled molecules into a tumor‐supplying artery for magnetic resonance spectroscopy (MRS) studies of tumor metabolism. read more here.
Keywords: arterial injection; metabolism; direct arterial; 13c labeled ... See more keywords
Carbon transfer from the submerged macrophyte Hydrilla verticillata to zooplankton: a 13C-labeled mesocosm study
Sign Up to like & getrecommendations! Published in 2021 at "Hydrobiologia"
DOI: 10.1007/s10750-021-04645-3
Abstract: Submerged macrophytes cannot be utilized directly by zooplankton. However, vegetation can serve as an organic carbon resource for heterotrophic bacteria, which are themselves accessible to zooplankton. We therefore hypothesize that submerged macrophytes supply a carbon… read more here.
Keywords: zooplankton; carbon; 13c labeled; verticillata zooplankton ... See more keywords
Analysis of Metabolic Pathways by 13C-Labeled Molecular Probes and HRMAS Nuclear Magnetic Resonance Spectroscopy: Isotopologue Identification and Quantification Methods for Medical Applications.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c00214
Abstract: The use of 13C-labeled molecular probes is essential to explore altered metabolic pathways in human pathologies. The analysis of the different 13C isotopologues resulting from these changes in metabolic pathways is essential to understand the… read more here.
Keywords: labeled molecular; 13c labeled; methodology; spectroscopy ... See more keywords
Use of Circular Statistics To Model αMan-(1→2)-αMan and αMan-(1→3)-α/βMan O-Glycosidic Linkage Conformation in 13C-Labeled Disaccharides and High-Mannose Oligosaccharides.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemistry"
DOI: 10.1021/acs.biochem.8b01050
Abstract: A new experimental method, MA' AT analysis, has been applied to investigate the conformational properties of O-glycosidic linkages in several biologically important mannose-containing di- and oligosaccharides. Methyl α-d-mannopyranosyl-(1→2)-α-d-mannopyranoside (2), methyl α-d-mannopyranosyl-(1→3)-α-d-mannopyranoside (3), and methyl α-d-mannopyranosyl-(1→3)-β-d-mannopyranoside… read more here.
Keywords: man man; linkage conformation; 13c labeled; circular statistics ... See more keywords
Untargeted Stable Isotope Probing of the Gut Microbiota Metabolome Using 13C-Labeled Dietary Fibers.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.1c00124
Abstract: The gut microbiome generates numerous metabolites that exert local effects and enter the circulation to affect the functions of many organs. Despite extensive sequencing-based characterization of the gut microbiome, there remains a lack of understanding… read more here.
Keywords: 13c labeled; gut microbiome; stable isotope; dietary fibers ... See more keywords
Understanding the Microstructure of Poly(p-phenylenevinylene)s Prepared by Ring-Opening Metathesis Polymerization Using 13C-Labeled Paracyclophanediene Monomers
Sign Up to like & getrecommendations! Published in 2018 at "Macromolecules"
DOI: 10.1021/acs.macromol.8b00705
Abstract: Selectively main chain 13C-labeled poly(p-phenylenevinylene)s (PPVs) were synthesized by ring-opening metathesis polymerization (ROMP) of 13C-labeled dialkoxy-substituted [2,2] paracyclophane-1,9-dienes (M) using the Grubbs second generation ruthenium carbene complex (G2). Analysis of the natural abundance and 13C-labeled… read more here.
Keywords: metathesis polymerization; poly phenylenevinylene; ring opening; 13c labeled ... See more keywords
Visualization of Partial Exocytotic Content Release and Chemical Transport into Nanovesicles in Cells
Sign Up to like & getrecommendations! Published in 2022 at "ACS Nano"
DOI: 10.1021/acsnano.2c00344
Abstract: For decades, “all-or-none” and “kiss-and-run” were thought to be the only major exocytotic release modes in cell-to-cell communication, while the significance of partial release has not yet been widely recognized and accepted owing to the… read more here.
Keywords: visualization partial; 13c labeled; partial release; partial exocytotic ... See more keywords
Harnessing 13C-labeled myo-inositol to interrogate inositol phosphate messengers by NMR† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc00151d
Sign Up to like & getrecommendations! Published in 2019 at "Chemical Science"
DOI: 10.1039/c9sc00151d
Abstract: The analysis of inositol poly- and pyrophosphates, an important group of eukaryotic messengers, is enabled by applying 13C-labeled inositol. read more here.
Keywords: inositol interrogate; 13c labeled; inositol; harnessing 13c ... See more keywords
METABOLISMS OF 13C IN CATTLE SEMITENDINOSUS MUSCLE AFTER ADMINISTRATION OF 13C LABELED ORCHARD GRASS.
Sign Up to like & getrecommendations! Published in 2022 at "Radiation protection dosimetry"
DOI: 10.1093/rpd/ncac083
Abstract: 14C released from nuclear facilities is transferred to cattle through their consumption of 14C contaminated grasses. To estimate the concentrations of 14C in their meat, we conducted two sets of experiments. In the first experiment,… read more here.
Keywords: 13c labeled; grass; metabolisms 13c; first experiment ... See more keywords
Abstract 371: Utilizing metabolic pathways to improve diagnosis and risk stratification of prostate cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-371
Abstract: Prostate cancer has well-characterized changes that take place metabolically in the citric acid cycle (CAC) such as increased lactate formation, reversal of physiologic buildup of citrate and breakdown into downstream CAC products. Metabolic MR spectroscopy… read more here.
Keywords: cancer; 13c labeled; 13c pyruvate; prostate cancer ... See more keywords
Endogenous synthesis of milk oleic acid in dairy ewes: In vivo measurement using 13C-labeled stearic acid.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of dairy science"
DOI: 10.3168/jds.2016-12097
Abstract: The use of stable isotopes is a reliable and risk-free alternative to radioactive tracers for directly examining in vivo fatty acid (FA) metabolism. However, very limited information is available in ruminants, and none is available… read more here.
Keywords: milk; 13c labeled; oleic acid; dairy ewes ... See more keywords