Hyperpolarized 13C magnetic resonance spectroscopy detects toxinâinduced neuroinflammation in mice
Sign Up to like & getrecommendations! Published in 2019 at "NMR in Biomedicine"
DOI: 10.1002/nbm.4164
Abstract: Lipopolysaccharide (LPS) is a commonly used agent for induction of neuroinflammation in preclinical studies. Upon injection, LPS causes activation of microglia and astrocytes, whose metabolism alters to favor glycolysis. Assessing in vivo neuroinflammation and its… read more here.
Keywords: resonance spectroscopy; magnetic resonance; neuroinflammation; hyperpolarized 13c ... See more keywords
Measuring glucose cerebral metabolism in the healthy mouse using hyperpolarized 13C magnetic resonance
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-12086-z
Abstract: The mammalian brain relies primarily on glucose as a fuel to meet its high metabolic demand. Among the various techniques used to study cerebral metabolism, 13C magnetic resonance spectroscopy (MRS) allows following the fate of… read more here.
Keywords: metabolism; cerebral metabolism; magnetic resonance; hyperpolarized 13c ... See more keywords