Articles with "13c mri" as a keyword



Hyperpolarized 13C MRI Reveals Large Changes in Pyruvate Metabolism During Digestion in Snakes

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Published in 2022 at "Magnetic Resonance in Medicine"

DOI: 10.1002/mrm.29239

Abstract: Hyperpolarized 13C MRI is a powerful technique to study dynamic metabolic processes in vivo; but it has predominantly been used in mammals, mostly humans, pigs, and rodents. read more here.

Keywords: reveals large; 13c mri; hyperpolarized 13c; large changes ... See more keywords

Direct and indirect assessment of cancer metabolism explored by MRI

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Published in 2018 at "NMR in Biomedicine"

DOI: 10.1002/nbm.3966

Abstract: Magnetic resonance‐based approaches to obtain metabolic information on cancer have been explored for decades. Electron paramagnetic resonance (EPR) has been developed to pursue metabolic profiling and successfully used to monitor several physiologic parameters such as… read more here.

Keywords: 13c mri; indirect assessment; direct indirect; cancer ... See more keywords

Rapid in situ carbon-13 hyperpolarization and imaging of acetate and pyruvate esters without external polarizer

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Published in 2024 at "Communications Chemistry"

DOI: 10.1038/s42004-024-01316-x

Abstract: Hyperpolarized 13C MRI visualizes real-time metabolic processes in vivo. In this study, we achieved high 13C polarization in situ in the bore of an MRI system for precursor molecules of most widely employed hyperpolarized agents:… read more here.

Keywords: hyperpolarization; system; mri; 13c mri ... See more keywords

IMG-117. Characterization of recurrent IDH-mutant glioma using multiparametric1H/Hyperpolarized-13C MRI and histopathological analysis

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Published in 2025 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noaf201.1196

Abstract: Isocitrate dehydrogenase (IDH)-mutant gliomas demonstrate metabolic reprogramming and remain challenging to assess using conventional MRI alone. 1H MR spectroscopic imaging (MRSI) of steady-state metabolism and real-time hyperpolarized carbon-13 (HP-13C) MRI of dynamic metabolism are of… read more here.

Keywords: mutant glioma; histopathology; 13c mri; idh mutant ... See more keywords

Assessment of early response to neoadjuvant chemotherapy in multi-site high-grade serous ovarian cancer using hyperpolarized-13C MRI

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Published in 2025 at "EJNMMI Research"

DOI: 10.1186/s13550-025-01219-5

Abstract: To evaluate the capability of hyperpolarized [1-13C] pyruvate MRI to predict pathologic response to neoadjuvant treatment in multi-site abdominopelvic disease of high-grade serous ovarian cancer (HGSOC) patients and to compare 13C MRI and [18F]-FDG PET/CT… read more here.

Keywords: hyperpolarized 13c; 13c mri; response; neoadjuvant chemotherapy ... See more keywords