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Synthesis of 13R,20-dihydroxy-docosahexaenoic acid by site-directed mutagenesis of lipoxygenase derived from Oscillatoria nigro-viridis PCC 7112.

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Published in 2020 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2020.09.079

Abstract: Lipoxygenases (LOXs) are implicated in the biosynthesis of pro- and anti-inflammatory lipid mediators involved in immune cell signaling, most of which catalyze peroxidation of polyunsaturated fatty acids by distinct regio- and stereoselectivity. Current reports suggested… read more here.

Keywords: lipoxygenase; 13r dihydroxy; docosahexaenoic acid; dihydroxy docosahexaenoic ... See more keywords