Articles with "1447 rho" as a keyword



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RKI-1447, a Rho kinase inhibitor, causes ocular hypotension, actin stress fiber disruption, and increased phagocytosis

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Published in 2018 at "Graefe's Archive for Clinical and Experimental Ophthalmology"

DOI: 10.1007/s00417-018-4175-6

Abstract: PurposeThis study investigated the hypotensive effect of RKI-1447, a Rho kinase inhibitor, in a porcine ex vivo pigmentary glaucoma model.MethodsTwenty-eight porcine anterior chambers were perfused with medium supplemented with 1.67 × 107 pigment particles/ml for 48 h before… read more here.

Keywords: phagocytosis; rki 1447; pigment; rho kinase ... See more keywords