Atorvastatin induces MicroRNA-145 expression in HEPG2 cells via regulation of the PI3K/AKT signalling pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2018.04.005
Abstract: The use of statins as a potential cancer drug has been investigated; however the molecular mechanisms involved in their anti-oxidant, anti-proliferative and anti-cancer effects remain elusive. In our study, we investigated the involvement of downstream… read more here.
Keywords: microrna 145; pi3k akt; expression hepg2; expression ... See more keywords
MiRNA-145-5p expression and prospective molecular mechanisms in the metastasis of prostate cancer.
Sign Up to like & getrecommendations! Published in 2021 at "IET systems biology"
DOI: 10.1049/syb2.12011
Abstract: The clinicopathological implication and prospective molecular mechanisms of miRNA-145-5p in the metastasis of prostate cancer (PCa) stand unclear. Herein, it is found that miRNA-145-5p expression was remarkably reduced in 131 cases of metastatic PCa than… read more here.
Keywords: mirna 145; metastasis; pca; metastatic pca ... See more keywords
MicroRNA‐145 regulates disabled‐2 and Wnt3a expression in cardiomyocytes under hyperglycaemia
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DOI: 10.1111/eci.12867
Abstract: MicroRNA‐145 (miR‐145) could protect cardiomyocyte apoptosis against oxidative stress and repair infarcted myocardium. Angiotensin II (Ang II), a pro‐inflammatory cytokine could modulate myocardial remodelling. However, the role of hyperglycaemia on miR‐145 expression in cardiomyocyte or… read more here.
Keywords: 145 regulates; mir 145; microrna 145; expression cardiomyocytes ... See more keywords