Accelerator mass spectrometry for quantification of micro- and therapeutic dose diclofenac in microdialysis samples.
Sign Up to like & getrecommendations! Published in 2022 at "Bioanalysis"
DOI: 10.4155/bio-2022-0064
Abstract: Background: Microdialysis sampling after drug microdosing may provide tissue pharmacokinetic data early in clinical drug development. However, low administered doses and small sample volumes pose an analytical challenge, particularly for highly protein-bound drugs. Materials &… read more here.
Keywords: mass spectrometry; accelerator mass; 14c diclofenac; quantification micro ... See more keywords