Articles with "14c mirogabalin" as a keyword



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Renal tubular transporter-mediated interactions between mirogabalin and cimetidine in rats

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Published in 2023 at "Xenobiotica"

DOI: 10.1080/00498254.2023.2174916

Abstract: Abstract Cimetidine at a clinical dosage decreased the renal clearance (CLr) of mirogabalin in humans by inhibition of renal secretion. Mirogabalin is a substrate of human OAT1/3, OCT2, MATE1 and/or MATE2-K. To clarify the mechanism… read more here.

Keywords: cimetidine; kidney; transporter; mirogabalin cimetidine ... See more keywords