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Published in 2023 at "Xenobiotica"
DOI: 10.1080/00498254.2023.2174916
Abstract: Abstract Cimetidine at a clinical dosage decreased the renal clearance (CLr) of mirogabalin in humans by inhibition of renal secretion. Mirogabalin is a substrate of human OAT1/3, OCT2, MATE1 and/or MATE2-K. To clarify the mechanism…
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Keywords:
cimetidine;
kidney;
transporter;
mirogabalin cimetidine ... See more keywords