Structural Fingerprints of an Intact Monoclonal Antibody Acquired under Formulated Storage Conditions via 15N Direct Detection Nuclear Magnetic Resonance.
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DOI: 10.1021/acs.jmedchem.0c00231
Abstract: Noninvasive evaluation of tertiary structures is fundamental to the research, development, and use of the biologics. However, few methodologies are currently available for evaluating large molecular weight (MW) biologics, such as therapeutic monoclonal antibodies (mAbs;… read more here.
Keywords: nuclear magnetic; magnetic resonance; detection nuclear; 15n direct ... See more keywords