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Structural Mechanism of Barriers to Interspecies Seeding Transmissibility of Full‐Length Prion Protein Amyloid

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Published in 2019 at "ChemBioChem"

DOI: 10.1002/cbic.201900218

Abstract: A puzzling feature of prion diseases is the cross‐species barriers. The detailed molecular mechanisms underlying these interspecies barriers remain poorly understood because of a lack of high‐resolution structural information on the scrapie isoform of the… read more here.

Keywords: 165 167; structural mechanism; prion; prion protein ... See more keywords