Efficacy and safety of 177Lu‑DOTATATE in patients with advanced pancreatic neuroendocrine tumours: data from the NETTER-R international, retrospective study
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DOI: 10.1007/s00259-022-05771-3
Abstract: NETTER-R aimed to determine the efficacy, safety and tolerability of 177Lu-DOTATATE in patients with progressive, advanced pancreatic neuroendocrine tumours (panNETs) using retrospective real-world data from multiple sites. This international study retrospectively included patients with panNETs… read more here.
Keywords: dotatate; efficacy safety; dotatate patients; 177lu dotatate ... See more keywords
Cost-effectiveness of Lutetium [177Lu] oxodotreotide versus best supportive care with octreotide in patients with midgut neuroendocrine tumors in France
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DOI: 10.1080/13696998.2020.1830286
Abstract: Abstract Background and aims In France, there are approximately 2,400 new cases of neuroendocrine tumors (NETs) annually. Peptide receptor radionuclide therapy with 177Lu-Dotatate plus long-acting repeatable [LAR] octreotide 30 mg has been shown to significantly improve… read more here.
Keywords: octreotide lar; 177lu dotatate; dotatate; midgut nets ... See more keywords
CTNI-53. SINGLE ARM, OPEN-LABEL, MULTICENTER PHASE II STUDY OF THE RADIONUCLIDE 177LU-DOTATATE (LUTATHERA) IN ADULTS WITH ADVANCED INTRACRANIAL MENINGIOMA
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-oncology"
DOI: 10.1093/neuonc/noaa215.219
Abstract: Meningiomas are the most common primary intracranial neoplasm. Once surgical and radiotherapeutic options are exhausted, there are no effective medical treatments available. A majority of meningiomas express somatostatin receptor 2 (SSTR2), representing a promising treatment… read more here.
Keywords: meningiomas; treatment; 177lu dotatate; dotatate ... See more keywords
P14.67 Somatostatin receptor targeted radioligand therapyin head and neck paraganglioma
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DOI: 10.1093/neuonc/noz126.302
Abstract: Surgical resection is the therapy of choice in head and neck paraganglioma. However, surgery is associated with significant morbidity depending on tumor size and localization. In case of progressive residual or recurrent disease, new and… read more here.
Keywords: therapy; 177lu dotatate; head neck;
Evaluation of Patient Transmission Factor Following the Administration of 177Lu-DOTATATE
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DOI: 10.1097/hp.0000000000001611
Abstract: Abstract 177Lu-DOTATATE is a radionuclide therapy that is FDA approved for the treatment of somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors. Treatment facilities are required to determine the maximum radiation dose from such subjects to the maximally… read more here.
Keywords: patient transmission; transmission factor; evaluation patient; 177lu dotatate ... See more keywords
The therapeutic efficacy of 177Lu-DOTATATE/DOTATOC in advanced neuroendocrine tumors
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DOI: 10.1097/md.0000000000019304
Abstract: Abstract Background: Somatostatin analog therapies showed great potential for patients suffering advanced neuroendocrine tumors (NETs). This study was aimed to evaluate the therapeutic efficacy of 177Lu-DOTATATE/DOTATOC (177Lu-octreotate/octreotide) peptide receptor radionuclide therapy (PRRT) in advanced or… read more here.
Keywords: dotatate; therapeutic efficacy; advanced neuroendocrine; response ... See more keywords
Assessment of early oxidative stress following the use of radiotheranostics agents 177Lu-PSMA for prostate cancer and 177Lu-DOTATATE for neuroendocrine tumors; radioprotective effect of vitamin C.
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DOI: 10.1097/mnm.0000000000001327
Abstract: BACKGROUND We aimed first to evaluate the early oxidative stress following radionuclide therapy (RNT) with 177Lu-PSMA and 177Lu-DOTATATE and second to evaluate the protective effect of vitamin C on oxidative stress. MATERIALS AND METHODS Prostate… read more here.
Keywords: group; treatment; 177lu dotatate; stress ... See more keywords
The prognostic role of whole-body volumetric 68GA-DOTATATE PET/computed tomography parameters in patients with gastroenteropancreatic neuroendocrine tumor treated with 177LU-DOTATATE
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DOI: 10.1097/mnm.0000000000001693
Abstract: Objective The aim of this study is to evaluate the prognostic role of Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 and quantitative 68Ga-DOTATATE PET/computed tomography parameters such as maximum standardized uptake value (SUVmax), mean… read more here.
Keywords: treated 177lu; 177lu dotatate; dotatate; 68ga dotatate ... See more keywords
177Lu-DOTATATE Therapy in Radioiodine-refractory Differentiated Thyroid Cancer: A Single Center Experience
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DOI: 10.1097/rlu.0000000000002219
Abstract: Introduction Patients with radioiodine-refractory differentiated thyroid cancer (RrDTC) have a rather poor prognosis and are in need of novel treatments. As RrDTCs can in some cases express somatostatin receptors (SSRT), targeting of these receptors by… read more here.
Keywords: refractory differentiated; 177lu dotatate; differentiated thyroid; dotatate ... See more keywords
177Lu-DOTATATE PRRT for Multiple Unusual Metastatic Sites in Neuroendocrine Tumor.
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DOI: 10.1097/rlu.0000000000004139
Abstract: ABSTRACT Thyroid gland and orbit are rare sites of metastases in neuroendocrine tumors. We present an extremely rare case of rectal neuroendocrine tumor with metastases to thyroid gland and intra-orbital regions that demonstrated significant reduction… read more here.
Keywords: dotatate prrt; neuroendocrine tumor; 177lu dotatate; prrt multiple ... See more keywords
A Case of Metastatic Thymoma Responsive to Treatment With 177Lu-DOTATATE.
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DOI: 10.1097/rlu.0000000000004553
Abstract: ABSTRACT We describe a case of a 74-year-old woman with germline BRCA2 mutation, with an incidental diagnosis of metastatic thymoma presenting as a mediastinal mass with cardiac muscle and lymph node involvement. Despite surgical and… read more here.
Keywords: 177lu dotatate; thymoma; case; treatment ... See more keywords