Targeted Radionuclide Therapy in Patient-Derived Xenografts Using 177Lu-EB-RGD
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DOI: 10.1158/1535-7163.mct-19-1098
Abstract: Currently, most patients with non–small cell lung cancer (NSCLC) are diagnosed in advanced stages with a poor five-year survival rate. Therefore, intensive research aimed at finding novel therapeutic strategies has been ongoing; experimental models that… read more here.
Keywords: 177lu rgd; rgd; pdx; patient derived ... See more keywords
Abstract 3946: Radiolabeled αvβ3 analog 177Lu-EB-RGD is an effective therapeutic agent in thyroid cancer xenograft mouse model
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3946
Abstract: Background: Integrins are cell adhesion receptors consisting of 18α and 8β subunits. A subset of integrins (αvβ3) recognizes Arg-Gly-Asp (RGD) peptide motifs which are involved in the neovascularization and progression of various cancers. The aim… read more here.
Keywords: 177lu rgd; analog 177lu; expression; thyroid cancer ... See more keywords