Deletion of IL-17ra in osteoclast precursors increases bone mass by decreasing osteoclast precursor abundance.
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DOI: 10.1016/j.bone.2021.116310
Abstract: Metabolic bone diseases, such as osteoporosis, typically reflect an increase in the number and activity of bone-resorbing osteoclasts that result in a loss of bone mass. Inflammatory mediators have been identified as drivers of both… read more here.
Keywords: bone; bone mass; 17ra osteoclast; osteoclast precursors ... See more keywords