Evaluation of [18F]PF-06455943 as a Potential LRRK2 PET Imaging Agent in the Brain of Nonhuman Primates.
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DOI: 10.1021/acschemneuro.2c00466
Abstract: Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the common causes of inherited Parkinson's disease (PD) and emerged as a causative PD gene. Particularly, LRRK2-Gly2019Ser mutation was reported to alter the early phase… read more here.
Keywords: evaluation 18f; brain; lrrk2; 18f 06455943 ... See more keywords