[18F]AV‐1451 clustering of entorhinal and cortical uptake in Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Neurology"
DOI: 10.1002/ana.25142
Abstract: To use a cluster analysis of [18F]AV‐1451 tau‐PET data to determine how subjects with Alzheimer's disease (AD) vary in the relative involvement of the entorhinal cortex and neocortex, and determine whether relative involvement of these… read more here.
Keywords: 1451 clustering; alzheimer disease; entorhinal cortical; 18f 1451 ... See more keywords
In Vivo cortical tau in Parkinson's disease using 18F‐AV‐1451 positron emission tomography
Sign Up to like & getrecommendations! Published in 2017 at "Movement Disorders"
DOI: 10.1002/mds.26961
Abstract: Background: Alzheimer's disease copathology is common in PD at autopsy. In non‐PD subjects with mild cognitive impairment, tau depositions can be detected using 18F‐AV‐1451 PET. We hypothesized that 18F‐AV‐1451 PET would show tau aggregation in… read more here.
Keywords: cortical tau; using 18f; vivo cortical; disease ... See more keywords
[18F] AV-1451 uptake in corticobasal syndrome: the influence of beta-amyloid and clinical presentation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neurology"
DOI: 10.1007/s00415-018-8815-x
Abstract: Corticobasal syndrome (CBS) is a phenotypic manifestation of diverse pathologies, including Alzheimer’s disease and 4-repeat tauopathies. Predicting pathology in CBS is unreliable and, hence, molecular neuroimaging may prove to be useful. The aim of this… read more here.
Keywords: 1451 uptake; cbs; beta amyloid; 18f 1451 ... See more keywords
[18F]AV-1451 binding to neuromelanin in the substantia nigra in PD and PSP
Sign Up to like & getrecommendations! Published in 2017 at "Brain Structure and Function"
DOI: 10.1007/s00429-017-1507-y
Abstract: This study investigated binding of [18F]AV-1451 to neuromelanin in the substantia nigra of patients with Parkinson’s disease (PD) and progressive supranuclear palsy (PSP). [18F]AV-1451 is a positron emission tomography radiotracer designed to bind pathological tau.… read more here.
Keywords: psp; neuromelanin substantia; binding; substantia nigra ... See more keywords
18F-AV-1451 positron emission tomography in Alzheimer’s disease and progressive supranuclear palsy
Sign Up to like & getrecommendations! Published in 2017 at "Brain"
DOI: 10.1093/brain/aww340
Abstract: The extent to which the tau tracer [18F]AV-1451 can differentiate between tauopathies is unknown. By comparing patients with Alzheimer’s disease and progressive supranuclear palsy (PSP), Passamonti et al. show that [18F]AV-1451 displays greater specificity for… read more here.
Keywords: supranuclear palsy; alzheimer disease; pathology; 18f 1451 ... See more keywords
Distinct 18F‐AV‐1451 tau PET retention patterns in early‐ and late‐onset Alzheimer's disease
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DOI: 10.1093/brain/awx171
Abstract: &NA; Patients with Alzheimer's disease can present with different clinical phenotypes. Individuals with late‐onset Alzheimer's disease (>65 years) typically present with medial temporal lobe neurodegeneration and predominantly amnestic symptomatology, while patients with early‐onset Alzheimer's disease… read more here.
Keywords: late onset; alzheimer disease; disease; 18f 1451 ... See more keywords
[18F]-AV-1451 binding profile in chronic traumatic encephalopathy: a postmortem case series
Sign Up to like & getrecommendations! Published in 2019 at "Acta Neuropathologica Communications"
DOI: 10.1186/s40478-019-0808-1
Abstract: IntroductionChronic traumatic encephalopathy (CTE) is a tauopathy associated to repetitive head trauma. There are no validated in vivo biomarkers of CTE and a definite diagnosis can only be made at autopsy. Recent studies have shown… read more here.
Keywords: tau; traumatic encephalopathy; 1451 binding; tau aggregates ... See more keywords