Novel 18F-labeled α-methyl-phenylalanine derivative with high tumor accumulation and ideal pharmacokinetics for tumor specific imaging.
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DOI: 10.1021/acs.molpharmaceut.9b00446
Abstract: Positron emission tomography (PET) imaging with 18F-labeled α-methyl-substituted amino acids exerts significant influence on differential diagnosis of malignant tumors and tumor-like lesions. Exclusive uptake via L-type amino acid transporter 1 (LAT1), a tumor specific transporter,… read more here.
Keywords: 18f labeled; methyl; tumor accumulation; 18f famp ... See more keywords