Comparison of 18F-FET PET and perfusion-weighted MRI for glioma grading: a hybrid PET/MR study
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-017-3812-3
Abstract: PurposeBoth perfusion-weighted MR imaging (PWI) and O-(2-18F-fluoroethyl)-L-tyrosine PET (18F–FET) provide grading information in cerebral gliomas. The aim of this study was to compare the diagnostic value of 18F–FET PET and PWI for tumor grading in… read more here.
Keywords: pet; fet pet; 18f fet; pet pwi ... See more keywords
18F-Fluoroethyl-tyrosine uptake is correlated with amino acid transport and neovascularization in treatment-naive glioblastomas
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-019-04407-3
Abstract: PurposeTo investigate the in vivo correlation between 18F-fluoroethyl-tyrosine (18F-FET) uptake and amino acid transporter expression and vascularization in treatment-naive glioblastomas.MethodsA total of 43 stereotactic biopsies were obtained from 13 patients with suspected glioblastoma prior to… read more here.
Keywords: correlation; amino acid; 18f fet; fet uptake ... See more keywords
Comparison of [18F]Fluoroethyltyrosine PET and Sodium MRI in Cerebral Gliomas: a Pilot Study
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Imaging and Biology"
DOI: 10.1007/s11307-019-01349-y
Abstract: PurposePositron emission tomography (PET) using O-(2-[18F]fluoroethyl)-L-tyrosine ([18F]FET) improves the diagnostics of cerebral gliomas compared with conventional magnetic resonance imaging (MRI). Sodium MRI is an evolving method to assess tumor metabolism. In this pilot study, we… read more here.
Keywords: pet; cerebral gliomas; 18f fet; sodium ... See more keywords
Diagnostic impact of additional O-(2-[18F]fluoroethyl)-L-tyrosine (18F-FET) PET following immunotherapy with dendritic cell vaccination in glioblastoma patients.
Sign Up to like & getrecommendations! Published in 2019 at "British journal of neurosurgery"
DOI: 10.1080/02688697.2019.1639615
Abstract: Objective: Vaccination therapy using tumour antigen-loaded, autologous dendritic cells (DC) is a promising therapeutic approach alongside standard treatment for glioblastoma (GBM). However, reliable diagnostic criteria regarding therapy monitoring are not established. Here, we analysed the… read more here.
Keywords: vaccination therapy; fet pet; 18f fet;
Identification of time-to-peak on dynamic 18F-FET-PET as a prognostic marker specifically in IDH1/2 mutant diffuse astrocytoma
Sign Up to like & getrecommendations! Published in 2018 at "Neuro-Oncology"
DOI: 10.1093/neuonc/nox153
Abstract: Background Stratification of glioma according to isocitrate dehydrogenase 1/2 (IDH1/2) mutation and 1p/19q codeletion status has gained major importance in the new World Health Organization (WHO) classification. Parameters derived from uptake dynamics of 18F-fluoro-ethyl-tyrosine PET… read more here.
Keywords: idh1 mut; fet pet; 18f fet; codel ... See more keywords
Characterization of Diffuse Gliomas With Histone H3-G34 Mutation by MRI and Dynamic 18F-FET PET
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DOI: 10.1097/rlu.0000000000002300
Abstract: Background Recent data suggest that diffuse gliomas carrying mutations in codon 34 of the H3 histone family 3A protein represent a very rare, distinct subgroup of IDH–wild type malignant astrocytic gliomas. However, characteristics detectable by… read more here.
Keywords: fet pet; 18f fet; diffuse gliomas;
Point Spread Function Reconstruction for Integrated 18F-FET PET/MRI in Patients With Glioma: Does It Affect SUVs and Respective Tumor-to-Background Ratios?
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Nuclear Medicine"
DOI: 10.1097/rlu.0000000000002423
Abstract: Purpose Semiquantitative 18F-FET PET assessment using the tumor's SUV or tumor-to-background ratios (TBRs) can separate gliomas from peritumoral tissue or progression from pseudoprogression. This study investigated if point spread function (PSF) reconstruction of 18F-FET PET… read more here.
Keywords: fet pet; 18f fet; tumor; background ratios ... See more keywords
Clinical Usefulness of 18F-FET PET in a Pediatric Patient With Suspected Demyelinating Disease.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000004201
Abstract: ABSTRACT An 11-year-old boy who presented with headache and progressive right-sided weakness exhibited cortical swelling in the parafalcine area of both frontoparietal high convexity and splenium portion of corpus callosum on brain MRI. This suggested… read more here.
Keywords: demyelinating disease; clinical usefulness; patient; 18f fet ... See more keywords
Towards standardization of 18F-FET PET imaging: do we need a consistent method of background activity assessment?
Sign Up to like & getrecommendations! Published in 2017 at "EJNMMI Research"
DOI: 10.1186/s13550-017-0295-y
Abstract: BackgroundPET with O-(2-18F-fluoroethyl)-L-tyrosine (18F-FET) has reached increasing clinical significance for patients with brain neoplasms. For quantification of standard PET-derived parameters such as the tumor-to-background ratio, the background activity is assessed using a region of interest… read more here.
Keywords: 18f fet; reader; background activity; background ... See more keywords
O-(2-[18F]fluoroethyl)-l-tyrosine PET in gliomas: influence of data processing in different centres
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DOI: 10.1186/s13550-017-0316-x
Abstract: BackgroundPET using O-(2-[18F]fluoroethyl)-l-tyrosine (18F-FET) is an established method for brain tumour diagnostics, but data processing varies in different centres. This study analyses the influence of methodological differences between two centres for tumour characterization with 18F-FET… read more here.
Keywords: data processing; fet pet; 18f fet; 18f fluoroethyl ... See more keywords
Reference values of physiological 18F-FET uptake: Implications for brain tumor discrimination
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0230618
Abstract: Purpose The aim of this study was to derive reference values of 18F-fluoro-ethyl-L-tyrosine positron emission tomography (18F-FET-PET) uptake in normal brain and head structures to allow for differentiation from tumor tissue. Materials and methods We… read more here.
Keywords: 18f fet; fet uptake; reference values; brain ... See more keywords